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Ana titr 1:160

ana titer 1 160 speckled Answers from Doctors HealthTa

A positive ANA titer blood test indicates the presence of an autoimmune disease. Additional testing is usually performed as a follow-up to help determine what specific disease may be present. Up to 95% of people who are eventually diagnosed with lupus, for example, have the first step of the diagnostic process be a positive ANA titer blood test ANA was positive, 1:160 titer, atypical speckled pattern. Wondering if I also now have Sjogren's or scleroderma. Comment from: Rose72, 25-34 Female (Patient) Published: January 24. I wonder if it is possible to have an autoimmune disease and have an ANA dilution test result of 40 titer. I have had issues with swollen, stiff and painful joints. 1:160 Titer ANA : Subscribe To Lupus Thread Tools: Search this Thread: 01-06-2004, 05:21 PM #1: Coreo Junior Member . Join Date: Jan 2004. Location: Los Angeles. Posts: 10 1:160 Titer ANA. I just learned of my ANA test results today. I understand the concept of this test. I don't know where 1:160 stands other than positive Not much by itself: An ANA of 1:160 is a low titter and can be seen in healthy people. The speckled pattern is commonly associated with lupus but is not enough to make a diagnosis especially when the titer is very low. Your doctor should look at all that is going on and help to determine if i is meaningful

The ANA test result can sometimes also be positive if you have one of these conditions: Raynaud's syndrome -- a disease that makes your fingers and toes turn blue and feel cold Thyroid diseases. 5% of the population will have a titer positive at 1:160 3% of the population will have a titer positive at 1:320 A titer of 1:160 or above is commonly considered a positive test result ANA is first reported at 1:40, then 1:80, then 1:160, 1:320, 1:640, 1:1280, 1:2560, etc. The higher it is, the less likely it is to be false-positive, I believe. The rheum will likely take a lifetime medical history, do new blood labs that include more specific tests that haven't been done yet, and urinalysis

I got a copy of my test results & confused. I read everything referring to titers like 1: 160 or something, mine just says ANA TITER result 80 (@a) ANA PATTERN result homogenous (@a), ana screen result says positive. ANY help or input please :-) My doctor seems to keep pushing me off. I feel like crap all the time For an ANA test, a member of your health care team takes a sample of blood by inserting a needle into a vein in your arm. The blood sample is sent to a lab for analysis. You can return to your usual activities immediately. Results. The presence of antinuclear antibodies is a positive test result. But having a positive result doesn't mean you. Antinuclear antibodies (ANA) are a group of autoantibodies produced by a person's immune system when it fails to adequately distinguish between self and nonself. The ANA test detects these autoantibodies in the blood. ANA react with components of the body's own healthy cells and cause signs and symptoms such as tissue and organ inflammation, joint and muscle pain, and fatigue

Anti-Nuclear Antibody (ANA) - RheumInf

  1. e came out as 7 with high rage of 14) (2 replies
  2. An ana test performed on 7.19/09 showed Homogeneous pattern 1:80 and then on 9/2/09 the pattern was 1:160 with speckled 1:160 too. My sed rate was 2 in july and 4 in Sept. C-T of chest showed granulomatous scarring with calcified lymph node in Bilateral hila and diffusely fatty liver
  3. A positive ANA test means that you have high levels of ANA in your blood. A positive ANA test is usually reported as both a ratio (called a titer) and a pattern, such as smooth or speckled

ana titer 1:160 - Multiple Sclerosis - MedHel

  1. I did test positive for hashimotos. A few weeks ago I was having really bad dry eye in one eye and had to pry it open in the mornings. My eye dr wanted to run a test for myasthenia gravis and it came back negative but he ran another ANA with it. This time, it came back positive and speckled again but the number doubled to 1:160
  2. PCP ran ANA test a week ago (last Friday) and nurse called Monday and said my ANA was negative. The previous ANA test (back in early June 2010) came back positive, 1:160, fine speckled. Now that was my GI doc interpreting the results because he was trying to figure out my unexplained anemia (iron and GI were ok)
  3. Usually, the results of the ANA test are reported in titers and patterns. The titer gives information about how many times the lab technician diluted the blood plasma to get a sample of ANAs. Each titer involves doubling the amount of test fluid, so that the difference between a titer of 1:640 and 1:320 is one dilution

1. Antinuclear Antibodies (ANA) normal is below 7.5 2. Antinuclear Antibodies Titer normal is below 1:40 Titer: measurement of the amount or concentration of a substance in a solution. Normal Range = < 1:40. A positive test means - Most patients with lupus will have a positive ANA test at some time in the course of their disease I tested positive for ANA, it is 1:160 with a speckled and homogenous pattern. I have symptoms of aches and pain in my knees and my hands. My second round of tests did not show any positive's for lupus, rh or any other disease. The doctor said I just need to take preventative measures to keep. Aches and pains at bay- rest, take warm baths, des. Titers ≥1:160 usually indicate the presence of active SLE, although occasionally other autoimmune disease may induce these high titers. There are now known groups of ANA-negative lupus patients. Such patients often have antibodies to SS-A/Ro antigen (usually when a frozen section substrate is used) and subacute cutaneous lupus

The IF ANA is generally screened at a dilution (e.g., titer) of 1:40, and, if positive, serial dilutions are carried out until a dilution is negative. Most labs titer to 1:1280, but some go higher. It is not clear whether titering higher is clinically useful, because the titer of an ANA usually does not correlate with clinical activity An ANA test is considered positive if fluorescence is seen at a titre of 1:40/1:80. Higher titres are more clinically significant as low positives (≤1:160) are found in up to 20% of healthy individuals, especially the elderly. Only around 5% of the healthy population have ANA titres of 1:160 or higher. HEp- Titers are usually low; less than 5% of healthy people have a titer of 1:160 or higher. Due to the low prevalence of SLE (50 cases per 100,000 persons) in the general population, the majority of persons randomly discovered to have a positive ANA result do not have SLE I just had more extensive bloodwork done and my ANA Titer was very high (1:160). This indicates that my body is attacking my tissues. I've read that Lyme can cause a similar result because of the Lyme is in the tissue and my body is fighting it...the ANA Titer would be elevated

In general, ANA titer of 1:160 on НЕр-2 or НЕр-2000 could be used for screening for . autoimmune rheumatic diseases. One major shortcoming of the method is the need This putatively normal population was ANA positive in 31.7% of individuals at 1:40 serum dilution, 13.3% at 1:80, 5.0% at 1:160, and 3.3% at 1:320. In comparison with the findings among the disease groups, a low cutoff point at 1:40 serum dilution (high sensitivity, low specificity) could have diagnostic value, since it would classify virtually.

what does a 1:160 ana titer mean? Yahoo Answer

  1. Thus a titer of 1:640 shows a greater concentration of ANA than 1:320 or 1:160, since it took 640 dilutions of the plasma before ANA was no longer detected. The apparent great difference between various titers can be misleading
  2. Frequency of ANA titer in all 355 patients. Among the 355 patients positive for ANA, 118 (33.2%) had an ANA titer ≥ 1:640 and 237 (66.8%) had an ANA titer < 1:640. Compared with the male patients (blank bar), a higher proportion of the female patients (77/271, 28.4%) were found to have an ANA titer ≥ 1:1,280. ANA = antinuclear antibody
  3. The ANA titer can indicate other diseases as well, depending on how the antibodies appear under the microscope. Check to see if the titers are increased, such as 1:320. This indicates that there are antibodies present and that the test is positive. If the number is low, then the test is negative and it is less likely that an autoimmune disease.
  4. I had an ANA test which the results are positive 1:160. I'm 23 yr Old female. Which autoimmune diseases can this be? Lupus?! I feel great the reason for the test was palpable lymph nodes. I've biopsied the node is was benign but now my ANA is. 1:160. I'm so scared

What is a positive ANA and what does it mean? - RheumDocto

Some data suggest that the titer of the ANA may help in distinguishing between patients with and without AARDs. In a study from 2011, Mariz et al. demonstrated that 45.8% of positive AN-As in healthy controls had a titer of 1:80, while 88.5% of ANA-positive AARD patients had an ANA titer ≥1:320 (7) {{configCtrl2.info.metaDescription} Hi there, I am new and this is my first post. I have tested consistently positive on my ANA test for the past three years. The pattern has always been homogeneous and the titer has changed from 1:160 to 1:3 and now back to 1:160. I live in a small town with a small town doctor so nothing has been done other than my research online

Video: ANA Titer Speckled Pattern 1:160 - Undiagnosed Symptoms

1:160 titer is detected. Conclusion: In this study, the screening titer of 1:160 for ANA test was confirmed by ROC Curve analyse. The screening titer of1:160, as proposed by ICAP. It has been proposed to study a large group including more population. Key Words: ANA, 1:160, titre, IFA, II Differential Diagnosis. Systemic lupus erythematosus (SLE): when active, usually a homogenous pattern on ANA or less commonly speckled, rim, or nucleolar when present in high enough titer to be. ANA reports include a titer (number) and a pattern. The titer tells us how many times the technician had to dilute plasma from the patient's blood to get a sample free of the anti-nuclear antibodies. Thus, a titer of 1:640 shows a greater concentration of anti-nuclear antibodies than a titer of 1:320 or 1:160 A and B, Distribution of antinuclear antibody (ANA)-positive healthy individuals (HI) and patients with autoimmune rheumatic disease (ARD) according to titer for all patterns combined on the ANA-HEp‐2 test (A) and for the nuclear fine speckled pattern on the ANA-HEp‐2 test (B).Data are presented as box plots, where the boxes represent the 25th to 75th percentiles, the lines within. One of the problems with ANA is that up to 20% of the population have low/medium titre (i.e. 1:40 - 1:400), particularly in people over the age of 50 and also in children. Further more ANA also appear transiently following major or minor illness. The specificity of the test therefore reflects the clinical picture of the patient and are most.

A speckled pattern in an anti-nuclear antibodies test may indicate Sjogren syndrome, scleroderma, polymyositis, rheumatoid arthritis or mixed connective tissue disease, according to Lab Tests Online. A speckled pattern may also appear on tests of individuals with systemic lupus, states the Johns Hopkins Lupus Center Some people use the ANA titer to support an immune-mediated pathogenesis in a variety of other diseases. For example, dogs with immune-mediated non-regenerative anemias often have high ANA titers (usually < 1:160), despite not having SLE. Interpretation guidelines for canine Antinuclear Antibody Test If the ANA Hep2 titer is ≥ 1:160 the following individual antinuclear antibodies will reflex. *Antibodies to: dsDNA, Smith, RNP, SSA, SSB, Scl 70, Centromere and Jo 1. *Individual ANA antibodies reflexed at a titer of 1:160 due to more clinical significance Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/ - With Picmonic, get your life back by studying less and remembering more. Med.. ANA screen, IFA, reflex titer/pattern, reflex multiplex 11-Ab cascade, with IdentRA Sub-panels that can be ordered separately include test code 91472 (dark green fill ), test code 249 (blue fill.

However, these false positive ANA's are usually of low titer and less that 1% of the normal population will have a titer of > or = 1:160. Usually the titer of the ANA test is >1:160 in the systemic connective tissue diseases. But neither the disease activity nor the patient's prognosis can be related to the titer of the ANA ANA Patterns - Cytoplasmic Patterns. Code Pattern Previous Nomenclature Description; AC-15. Cytoplasmic fibrillar linear. actin-like. This pattern is characterized by decorated cytoskeletal fibers, sometimes with small, discontinuous granular deposits. Typical staining show striated actin cables spanning the long axis of the cells. e.g. anti. NAIFA : Measurement of antinuclear antibodies (ANA) in serum is the most commonly performed screening test for patients suspected of having a systemic rheumatic disease, also referred to as connective tissue disease.(1) ANA occur in patients with a variety of autoimmune diseases, both systemic and organ-specific. They are particularly common in the systemic rheumatic diseases, which include. The titer shows how many times the technician had to mix fluid from the patient's blood to get a sample free of ANAs. Thus a titer of 1:640 shows a greater concentration of ANA than 1:320 or 1:160, since it took 640 dilutions of the plasma before ANA was no longer detected. The apparent great difference between various titers can be misleading Say that your ANA blood test results show a titer of 1:80. This means that 1 part of blood sample was diluted with 80 parts of salt solution before the antibodies activities were no longer detected! The normal range of ANA blood test varies from laboratory to laboratory

Ana Titer 1 80 . Ana Speckled Pattern 1 80 Meaning . Positive Ana Titer 1.160 Homogeneous . Ana Titer 1 160 Speckled Pattern Means . Ana Titer Range Table . Ana Test Results 1 160. Positive Ana 1 80 Speckled . Antinuclear Antibody Titer 1 160 linical significance of anti-MSA patterns in a Colombian population. During 2013 and 2014, 113,491 consecutive determinations of ANA were studied for the presence of uncommon patterns. Clinical and laboratory data of anti-MSA positive patients were retrospectively collected and analyzed. Of the 113,491 patients tested, 60,501 (53%) were positive for ANA, of which 834 (1.3%) were positive for. Hi, This is my first post and I am in the undiagnosed phase, trying to figure out what is going on with me. I had a mildly positive ANA with a centromere pattern 1:160. So far my symptoms are arthritic and numb fingers, Raynauds, achy hands, feet and joints; and some burning sensations. I went to.. The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to. Expect a complete medical history and examination along with the ANA test results to confirm and identify the specific type of autoimmune disease. In some individuals, a high ANA titer is normal. Consider other diseases associated with a high ANA titer such as rheumatoid arthritis, scleroderma, juvenile rheumatoid arthritis and Raynaud's syndrome

RACGP - Antinuclear antibody tes

  1. Although IIF using Hep-2 cells (IIF HEp2) is considered the gold standard for ANA testing, findings regarding the optimal titer and sensitivity in patients with SLE have been mixed. 9 To elucidate these matters, the investigators in the present study conducted a systematic review and meta-regression analysis of articles published between 1990.
  2. test for ANA at a titer of ≥1:80 in 8% of cases, of which 4% had a titer of ≥1:160. One HC was positive for ANA at a titer of 1:1280 (FS pattern). None of these HCs had any signs or symptoms that suggested connective tissue diseases and none took regular medicine that could cause a positive ANA test
  3. Dr. Jack Cush for RheumaKnowledgy.co
  4. Titers ≥ 1:160 usually indicate the presence of active SLE, although occasionally other autoimmune disease may induce these high titers. There are now known groups of ANA-negative lupus patients. Such patients often have antibodies to SS-A/Ro antigen (usually when a frozen section substrate is used) and subacute cutaneous lupus
  5. ANA is reported as a titer. Low titers are in the range of 1:40 to 1:60. A positive antinuclear antibody (ANA) test is of much more importance if you also have antibodies against the double-stranded form of DNA. The presence of antinuclear antibody (ANA) does not confirm a diagnosis of systemic lupus erythematosus (SLE). However, a lack.
  6. A titer of 1:160 is taken as significant for the diagnosis of CTDs in majority of laboratories [29, 30]. Although IF-ANA test is widely used and considered to be gold standard still the results may sometimes be misinterpreted

The lower, the dilution ratio at which ANA can be detected, the higher the titer and the presence of antibodies in the body. ANA is found in around 5% of the healthy adult population, being more present in women, especially above the age of 65. But that does not point to an autoimmune disease is present. Titers of 1:80 or lower are considered. The ANA test was designed by Dr. George Friou in 1957. The ANA test is performed using a blood sample. An ANA test is performed by testing the blood in the laboratory. The antibodies in the serum of the blood are exposed in the laboratory to cells. It is then determined whether or not antibodies are present that react to various parts of the. Elevated anti-nuclear antibody ANA level can have various causes, ranging in severity from 'needs attention' to 'very serious'. Finding the true cause means ruling out or confirming each possibility - in other words, diagnosis The problem with the ANA is that it can be found in normal healthy people. ANA 1:40 is found in 20 - 30% of healthy people; ANA 1:80 is found in 10 - 15% of healthy people, and ANA 1:160 found in 5% of healthy people. Up to 70% of people aged above 70 years have a positive ANA ANA in Rheumatic Diseases. Lupus - When the test is positive it highly shows that one is suffering from an autoimmune condition like lupus.This is a disease that destroys joints, one's skin and other body organs. A 95 percent of all persons having this disease will have a positive test result for antinuclear antibodies

ANA Titer Blood Test Results Fully Explained - HR

Titer: 1:160, 1:320, etc. Mønster Antistof specificiteter Hyppigste sygdomsassociationer Centromer Centromere n = 253 > 0,7 > 1,0 1: 160 ECS+IIF Sensitivity 91 85 89 92 Specificity 94 96 89 80 LR+ 15 21 7 4,5 ANA skal kun rekvireres ved symptomer på immuninflammatorisk bindevævssygdom. Ta Different connective tissue diseases are associated with a different frequency of ANA positivity (see the image below). An antibody pattern is reported with a positive titer and gives an indication of the likely diagnosis (see the image below). Pattern interpretation is subjective and thus frequently not specific for any individual disease state Steps in positive vs. negative: Step #1 is to see if there is an ANA reaction at a certain cut-off level or HIGHER. This step #1 is expressed in numbers so that the reaction can be mentally classified as weakly (1+) reactive (titer of 1:40-1:160), moderately (2+) reactive (1:320-1:640), or strongly (3+) reactive (higher than 1:640) ANA Patterns - Nuclear Patterns. Code Pattern Previous Nomenclature Description; AC-1. Nuclear homogeneous. Diffuse. Homogeneous and regular fluorescence across all nucleoplasm. The nucleoli maybe stained or not stained depending on cell substrate. Mitotic cells (metaphase, anaphase, and telophase) have the chromatin mass intensely stained in a. my 6 year old daughter was seen for reoccuring joint pain and low grade fever. she had a +ana (titer 160) and a centromere pattern. i was told that healthy people can have a + ana, but she is being sent to a specialist to rule out jra or lupus. the only research i could find about a centromere pattern says it is only seen in crest syndrome

ANA Titer 1:160 ANCA Proteinase-3 AB <6 (negative) ANCA Myeloperoxidase <6 (negative) TSH 1.45 (normal) B12 853 (normal) ESR 5 (normal) Protein Electrophoresis (all normal)-----Total Protein 7.7 Albumin 3.8 Alpha 1 Globulin 0.3. The titer shows how many times the solution was mixed with fluid from the patient's blood to get a sample free of ANAs. So a titer of 1:640 shows a greater concentration of ANA than 1:320 or 1:160, since it took 640 dilutions of the plasma before ANA was no longer detected. A negative ANA is any number LESS than 1:80 (this is one to 80 parts)

The antinuclear antibody (ANA) test is commonly used to look for autoantibodies that attack components of your cells' nucleus, or command center, triggering autoimmune disorders like lupus. 95% of people with lupus test positive for ANA, but a number of other, non-lupus causes can trigger a positive ANA, including infections and other autoimmune diseases. The [ ana titer 1 high, The ANA titer can indicate other diseases as well, depending on how the antibodies appear under the microscope. Check to see if the titers are increased, such as 1:320. This indicates that there are antibodies present and that the test is positive Sjögren's syndrome (SS) is a chronic (long-term) disease that affects the body's moisture-producing glands and causes a reduction in a variety of body fluids. The most common glands that are affected by Sjögren's are the tear glands and salivary glands. People with Sjögren's often have dry eyes that can feel gritty and suffer from dry [

Antinuclear Antibody Test Normal Range & Interpretation

A study41 involving 15 international laboratories found that ANA tests in the general population were positive in 32 percent of persons at a 1:40 dilution and in 5 percent of persons at a 1:160. Her ANA is 1/160, speckled pattern. Anaemia, low platelets, neutropenia Photosensitivity, rashes, alopecia, Raynauds, acrocyanosis, mouth ulcers Recurrent late miscarriage, IUGR, recurrent or unexpected thromboembolic disease Synovitis, tendonitis (90% have some degree of joint involvement If ANA positive at any titer but with any red flag symptoms, please refer to Rheumatology. Titer results ANA 1:160 or 1:320. Title: PowerPoint Presentation Author: Ness, Kathryn D Created Date I have several signs of lupus: . ANA of 1:160 - speckled pattern . A VERY large amount of protein in urine (creatinine ratio = 888.9 when it should be less than 30. . Significant joint pain . A rash on the face that I'm not sure is or is not lupus related.. The laboratory reports the quantity of ANA as a titre (the higher the titre the more times the sample can be diluted and ANA still be detected) 1:80 is a low titre, 1:160 is a high titre. The pattern of staining is also reported (eg homogenous, speckled, centromere patterns) as this may guide further tests that are associated with particular.

ANA Patterns: NEGATIVE PATTERN This serum sample is negative for anti-nuclear and anti-cytoplasmic antibodies at a 1:40 dilution on a human epithelial cell substrate (Hep-2 cells). High Titer (greater than 1:80) Homogeneous High titered (1:160 or greater) homogeneous pattern is suggestive of idiopathic or drug induced SLE In a separate study of 59 pediatric patients with fibromyalgia, 17 (28.8%) were ANA positive (mean titer 1:160). Fifty patients were followed for a mean of 18.3 months and during that time no patient developed a connective tissue disease . We would conclude from these findings that only rarely is the presence of ANA the harbinger of occult SLE. False-positive ANAs (i.e., ANAs in the absence of autoimmune disease or other diseases) are commonly found in normal women, elderly individuals, and first-degree relatives of patients with ANA-positive autoimmune diseases (typically in low titer). There are several important points about ANA that should be considered in the clinical setting ANA antibodies are the most common antibodies and may precede the onset of connective tissue disease. Although certain antibodies may show specificity for certain diseases (eg, SSA 52, SSA 60, and SSB antibodies for Sjögren syndrome), ANA antibodies are not specific for connective tissue disease, and may also be associated with infectious.

ANA at a titer of ≥1 : 160 were found in 11 of 12 lupus pleuritis samples, and in four of 42 pleural effusions from non-systemic lupus erythematosus (SLE) patients. The pleural effusion ANA at a. Antinukleární protilátky (ANA) Stanovení ANA je vyhledávacím testem při vyšetřování antinukleárních protilátek. Antigenem v imunofluorescenční reakci jsou úplná buněčná jádra, jako substrát používáme tkáňovou linii HEp-2

Healthboards - Immune & Autoimmune - Lupus: 1:160 Titer ANA

An positive ANA (antinuclear antibody) means that you make antibodies that attack the circulating debris of the nucleii of your own cells that have died. A titer of 320 means that your blood had. In 11 of 13 patients with lupus pleuritis, the pleural fluid ANA titer was ≥1:160, and nine of 13 patients with lupus pleuritis, the pleural fluid to serum ANA ratio was ≥1 . Of the nine patients in whom total hemolytic complement values were determined, five had low values (<20 units/ml), while four had normal values A high ANA is commonly found in healthy people and not a significant finding on it's own. I assume you meant to type 1:160 which is very low and just barely positive. Its definitely the cautious/appropriate choice for him to refer you to see a rheumatologist but a low positive ANA on it's own is a relatively non-chalant thing ANA is a screening test, since almost all patients with lupus have a strongly positive test. ANA is measured in how strongly it is positive, usually measured as 0 to 4+ or as a titer (the number of times a blood sample can be diluted and still be positive). ANA of 0, 1+ or 2+, or titers less than 1:80 (diluted 80 times) are usually unimportant

what does a positive ana 1:160 with speckled pattern mean

ANA has a sensitivity of 99%. A negative ANA test almost excludes the active SLE. This test may be positive in unrelated diseases of the patients. Around 20% of the normal population has a titer of 1:40. Around 5% of the normal population may have a titer of 1:160; When the cutoff titer is 1:40 then specificity is around 80% Tan et al, (5) in a study of healthy adults (age 20 to 60 years), found that 31.7% had a positive ANA result at a 1:40 dilution, 13.3% at a 1:80 dilution, 5% at a 1:160 dilution, and 3.3% at a 1. What is an ANA (antinuclear antibody) test? An ANA test looks for antinuclear antibodies in your blood. If the test finds antinuclear antibodies in your blood, it may mean you have an autoimmune disorder.An autoimmune disorder causes your immune system to attack your own cells, tissues, and/or organs by mistake

Antinuclear Antibodies (ANA) Test: Results, Positive vs

Low Vitamin D Levels with a Positive ANA Result by: Anonymous This is in response to the administrator's reply. Do you have high ANA and Vitamin D deficiency? Just curious how you know that a gluten free diet will solve all of the problems. Does it get rid of high ANA? I have been told by a microbiologist that once you have ANA it's in your.

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